4.5.6 Skin is a derm-approved skincare brand dedicated to melanin-rich skin. We built the world's first Skin Tone Research Lab in France to create effective solutions for the top concerns of darker skin tones: hyperpigmentation, dryness, dullness, and acne.

Our research dives deep into the science of skin tone and how genetics, metabolism and physiology impacts skin behaviour.

Here’s what makes us different:

✅ Original formulations, no generic repackaging
✅ Rigorous testing on darker skin
✅ Safe, natural, anti-inflammatory ingredients
✅ No harsh chemicals, nano-plastics, or synthetic preservatives

The foundation of our skin tone science uses a dermatological system called the Fitzpatrick scale, where phototypes are categorized based on the amount of the melanin pigment in skin. 4.5.6 Skin’s formulas are based on the unique functional and physiological differences of phototypes IV, V, and VI. 

Join our mission and understand your skin for the first time.